Role of microRNAs in intervertebral disc degeneration (Review)
نویسندگان
چکیده
منابع مشابه
Degeneration of the intervertebral disc
The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body. It is believed to be important clinically because there is an association of disc degeneration with back pain. Current treatments are predomina...
متن کامل*Running title: Role of HTRA1 in intervertebral disc degeneration
From the Bone and Stem Cell Research Group, CABMM, University of Zurich, 8057 Zurich, Switzerland, Spine Research Group, CABMM, University of Zurich, 8057 Zurich, Switzerland, Centre for Medical Biotechnology, Faculty of Biology and Geography, University Duisburg-Essen, 45117 Essen, Germany, Institute of Physiology and Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich,...
متن کاملIntervertebral Disc Dynamics and Degeneration
Degenerative disc disease is a serious health problem worldwide, whose etiological basis – mechanical stimulus, biochemical changes, or natural aging – is poorly understood. While the disc’s known function is that of dynamic shock absorber, its dynamic response has not been fully characterized throughout the disc health spectrum (from healthy to degenerate). Therefore, this study aimed to corre...
متن کاملincidence of microscopic lumbar intervertebral disc calcification and its correlation to endplate degeneration type and disc histopathologic angiogensis
چکیده ندارد.
15 صفحه اولStem cell horizons in intervertebral disc degeneration
Intervertebral disc degeneration remains a pervasive and intractable disease arising from a combination of aging and stress on the back and spine. The growing field of regenerative medicine brings the promise of stem cells in the treatment of disc disease. Scientists and physicians hope to employ stem cells not only to stop, but also reverse degeneration. However, there are many important outst...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2021
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2021.10292